In the News
Protocol OC-1901AR (Argentina arm of the original OC-1901 study) has received approval to proceed from the regulatory authority (ANMAT) and enrollment is open!
Clinical study details and site contacts can be located here: OC-1901AR Argentina | Clinicaltrials.gov Listing
OA Angioplasty in Tokyo
Dr. Ivan Lylyk of Buenos Aires, Argentina presented the compassionate use case series data associated with ophthalmic artery angioplasty in the treatment of late-stage AMD to physicians from around the world, attending the World Federation of Interventional and Therapeutic Neuroradiology meeting in Tokyo, Japan.
OA Angioplasty in Bogotá
Drs. Ivan Lylyk and Anibal Francone of Buenos Aires, Argentina presented their compassionate use case series data associated with ophthalmic artery angioplasty in the treatment of late-stage AMD. They brought their novel experiences to the physicians attending the Curso International de Oftalmologia (International Course of Ophthalmology) meeting in Bogata, Columbia where it was met with enthusiasm and lively discussion.
Retinal Deposits and Cardiovascular Disease
Robert Thompson and his colleagues at Mt. Sinai in NYC published their study evaluating the presence of subretinal drusenoid deposits (also known as reticular pseudo-drusen) and soft drusen, their two pathways to advanced AMD, associated genetic risk alleles, and underlying cardiovascular disease. These authors demonstrated that subretinal drusenoid deposits are associated with cardiovascular disease, stroke, lower HDL, and ARMS2 risk allele (well known to be associated with AMD). In addition, those with soft drusen were associated with higher HDL, CFH risk allele (also known to be associated with AMD), and two lipid risk genes. The data suggests that soft drusen and subretinal drusenoid deposits found in the retina, may well be markers for distinct disease.
Retinal specialist Philip J Rosenfeld, MD from Bascom Palmer Institute presented his poster at the annual meeting for The Association for Research in Vision and Ophthalmology (ARVO) in New Orleans, LA. These results are part of an ongoing prospective study demonstrating visual acuity in normal eyes, AMD eyes with drusen, and AMD eyes with non-foveal GA correlate with decreased perfusion (blood flow) of the choriocapillaris. Normal luminance VA (normal vision), low luminance VA (dim light vision), and the low luminance deficit (the difference between normal and dim light vision) all correlate with the choroidal choriocapillaris perfusion. This is an ongoing study which provides the missing link between decreased choriocapillaris perfusion and visual function.
Journal of NeuroInterventional Surgery
Drs. Lylyk and Lylyk from the ENERI medical institution in Buenos Aires are once again “In the News!” They have participated in an SNIS Insights online webinar for the Journal for NeuroInterventional Surgery (JNIS) Journal Club with renowned retinal specialist Philip J Rosenfeld, MD from the Bascom Palmer Eye Institute, to discuss ophthalmic artery angioplasty in the treatment of AMD. An interesting discussion ensued, providing insight from both Interventional Radiology and Ophthalmology perspectives.
This webinar followed presentations at top Interventional Neuroradiology medical conferences around the globe where Drs. Lylyk discussed the data associated with their compassionate use case series of patients.
- Semana Del Intervencionismo Mínimamente Invasivo (SIMI)
Buenos Aires, Argentina | December 2020
- Society of NeuroInterventional Surgery (SNIS)
Colorado Springs, Colorado USA | July 2021
- Brazilian Society of INR & Endovascular Surgery (SOBRICE)
São Paulo, Brazil | October 2021
- Brain Research and Advanced Interventional Neuroradiology (BRAIN)
London, United Kingdom | December 2021
- SNIS Insights: Online Webinar Series | JNIS Journal Club
Recorded | Thursday | March 3, 2022
Ophthalmic Artery Angioplasty
First published report of Dr. Pedro Lylyk’s case series of ophthalmic artery angioplasty performed in the treatment of patients with AMD. This case series took place at the acclaimed ENERI medical institution in Buenos Aires, Argentina, one of the most advanced medical facilities in the world!
Updated Insight into the Hemodynamic Model of AMD
Ophthalmic experts are rethinking the hemodynamic model of Age Related Macular Degeneration (AMD). Dr. Philip J Rosenfeld and colleagues dive into this topic, providing a contemporary take on a decades old theory.
An Update on the Hemodynamic Model of Age-Related Macular Degeneration | American Journal of Ophthalmology
Martinos Center Blood Flow Study
Hemodynamics experts at the Martinos Center publish outcomes of the study conducted with OcuDyne, evaluating altered blood flow in patients with and without AMD.
Altered Blood Flow in the Ophthalmic and Internal Carotid Arteries in Patients with Age-Related Macular Degeneration Measured Using Noncontrast MR Angiography at 7T | American Journal of Neuroradiology
Research enrollment is once again halted in Melbourne, Australia due to the COVID-19 Delta variant as Australia returns to lock-down.